AS-8351

Cannot supply to this region.

SKU:: SIH-558
Additional Names:: AS8351, 2-Hydroxy-1-naphthylaldehyde isonicotinoylhydrazone; NSC-51355, N'-[(Z)-(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxonaphthalen-1-ylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]pyridine-4-carbohydrazide, N'-[(Z)-(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide, N'-[(2-oxo-1-naphthylidene)methyl]-4-pyridinecarbohydrazide,
Molecular Weight:: 291.3
Purity:: >98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 796-42-9
ABP:: No Import Docs
Extra Details:: AS-8351 is a selective inhibitor of lysine-specific demethylase 1 (LSD1/KDM1A), an epigenetic regulator involved in chromatin remodeling and gene expression. In neurodegenerative disease research, LSD1 inhibition is being explored for its potential to modulate neurogenesis, synaptic plasticity, and memory formation. AS-8351 is used to study the impact of histone demethylation on neuronal differentiation and survival, particularly in models of Alzheimer's disease and cognitive decline. Its role in epigenetic regulation makes it a promising compound for investigating transcriptional dysregulation in the aging brain.