SIH-551
Filipin III
Cannot supply to this region.
- SKU:
- SIH-551
- Additional Names:
- Filipin, FILIPIN III, (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, Filimirasin, Desoxylagosin
- Molecular Weight:
- 654.83
- Purity:
- >98%
- Source:
- Streptomyces filipinensis
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 480-49-9
- ABP:
- No Import Docs
- Extra Details:
- Filipin III is a polyene macrolide that binds to unesterified cholesterol, disrupting membrane microdomains and lipid rafts. In neurodegenerative disease research, Filipin III is commonly used as a fluorescent probe to visualize cholesterol accumulation, particularly in Niemann-Pick type C disease. Its role in studying cholesterol trafficking and lysosomal storage disorders makes it a critical reagent in neuroscience and cellular pathology.
- Shipping Conditions:
- Ambient