SIH-542
NSC59984
Cannot supply to this region.
- SKU:
- SIH-542
- Additional Names:
- NSC59984, NSC-59984, NSC59984, MLS000737358, SMR000528276, (E)-1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one, 803647-40-7, AC1NS9AU, CID 5356520, MLS000737358, 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine, 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one
- Molecular Weight:
- 265.3
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 803647-40-7
- ABP:
- No Import Docs
- Extra Details:
- NSC59984 is a small molecule that restores wild-type p53 signaling in tumor cells by modulating the mutant p53/MDM2 pathway. Although its primary application is in oncology, the compound's ability to influence p53-mediated apoptosis and DNA repair pathways may have relevance in neurodegenerative disease models, where p53 dysregulation contributes to neuronal loss. Its selective cytotoxicity in cancer cells while sparing healthy cells also highlights its potential for targeted therapeutic development.
- Shipping Conditions:
- Ambient