SIH-534
Leptomycin B
Cannot supply to this region.
- SKU:
- SIH-534
- Additional Names:
- Elactocin, LMB, Mantuamycin, NSC 364372
- Molecular Weight:
- 540.7
- Purity:
- >99%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 87081-35-4
- ABP:
- No Import Docs
- Extra Details:
- Leptomycin B is a potent inhibitor of nuclear export proteins, specifically targeting CRM1/exportin 1. By blocking the nuclear export of tumor suppressors and regulatory proteins, it has been studied extensively in cancer research. In neuroscience, its ability to modulate nuclear-cytoplasmic transport has implications for neurodegenerative diseases where protein mislocalization contributes to pathology. Leptomycin B serves as a valuable tool in understanding nucleocytoplasmic dynamics in neuronal cells.
- Shipping Conditions:
- Ambient