SB431542

Cannot supply to this region.

SKU:: SIH-511
Additional Names:: SB 431542, 4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamide hydrate, 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide hydrate, 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamide hydrate
Molecular Weight:: 384.4
Purity:: ≥98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 301836-41-9
ABP:: No Import Docs
Extra Details:: SB431542 is a selective inhibitor of the TGF-B Beta type I receptor ALK5, as well as ALK4 and ALK7. TGF-B Beta signaling plays a complex role in neuroinflammation, neurogenesis, and synaptic plasticity. In neurodegenerative disease models, SB431542 has been used to modulate glial activation and to investigate the role of TGF-B Beta in neuronal survival and repair. Its application in stem cell research also supports its relevance in regenerative neuroscience.