SIH-508
PMA
Cannot supply to this region.
- SKU:
- SIH-508
- Additional Names:
- Phorbol 12-myristate 13-acetate
- Molecular Weight:
- 616.8
- Purity:
- ≥99%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 16561-29-8
- ABP:
- No Import Docs
- Extra Details:
- PMA is a potent phorbol ester widely used as a reversible activator of protein kinase C (PKC). In neuroscience, PMA serves as a critical tool for studying synaptic plasticity, signal transduction, and neuroinflammation. By mimicking diacylglycerol, PMA activates PKC isoforms, influencing neuronal gene expression, neurotransmitter release, and long-term potentiation. Its ability to modulate neuroinflammatory pathways and glial activation makes it relevant in models of neurodegenerative diseases such as Alzheimer's and Parkinson's. PMA is also used to investigate tumor-promoting mechanisms in neural tissues, offering insights into brain cancer biology.
- Shipping Conditions:
- Ambient