SIH-504
LY364947
Cannot supply to this region.
- SKU:
- SIH-504
- Additional Names:
- LY 364947, HTS 466284, ALK5 Inhibitor I, 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-quinoline, HTS 466284, Transforming Growth Factor-B Beta Type I Receptor Kinase Inhibitor
- Molecular Weight:
- 272.3
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 396129-53-6
- ABP:
- No Import Docs
- Extra Details:
- LY364947 is a potent and selective inhibitor of TGF-B Beta type I receptor kinase, blocking downstream SMAD signaling. TGF-B Beta signaling is involved in neuroinflammation, synaptic plasticity, and glial activation-processes central to neurodegenerative disease progression. LY364947 has been used to investigate the role of TGF-B Beta in central nervous system disorders, offering insights into therapeutic strategies targeting neuroinflammatory pathways.
- Shipping Conditions:
- Ambient