SIH-501
GDC 0941
Cannot supply to this region.
- SKU:
- SIH-501
- Additional Names:
- Pictrelisib, Pictilisib, GNE 0941, 2- (1H- indazol- 4- yl)- 6- [[4- (methylsulfonyl)- 1- piperazinyl]methyl]- 4- (4- morpholinyl)- thieno[3, 2- d]pyrimidine
- Molecular Weight:
- 513.63
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 957054-30-7
- ABP:
- No Import Docs
- Extra Details:
- GDC 0941 is a potent and selective inhibitor of class I phosphoinositide 3-kinases (PI3Ks), including PI3KA Alpha, B Beta, D Delta, and G Gamma isoforms. While primarily investigated in oncology for its role in inhibiting tumor growth and survival pathways, PI3K signaling is also critical in neuronal function, synaptic plasticity, and neuroinflammation. GDC 0941's modulation of PI3K pathways presents potential applications in neurodegenerative disease models, particularly those involving dysregulated cell survival and neuroimmune responses.
- Shipping Conditions:
- Ambient