SIH-500
Dovitinib
Cannot supply to this region.
- SKU:
- SIH-500
- Additional Names:
- 4- amino- 5- fluoro- 3- [6- (4- methyl- 1- piperazinyl) - 1H- benzimidazol- 2- yl] - 2(1H) - quinolinone
- Molecular Weight:
- 392.4
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 405169-16-6
- ABP:
- No Import Docs
- Extra Details:
- Dovitinib is a multi-targeted receptor tyrosine kinase inhibitor with activity against FLT-3, c-KIT, VEGFR, PDGFRB Beta, and CSF-1R. While primarily investigated for its anti-cancer properties, Dovitinib's inhibition of VEGFR and PDGFRB Beta has implications for neurovascular health and neuroinflammation. These pathways are increasingly recognized in the pathophysiology of neurodegenerative diseases, including Alzheimer's and Parkinson's. By modulating angiogenic and inflammatory signaling, Dovitinib may offer neuroprotective benefits and serve as a tool for studying neurovascular dysfunction in disease models.
- Shipping Conditions:
- Ambient