SIH-497
BRD 7389
Cannot supply to this region.
- SKU:
- SIH-497
- Additional Names:
- BRD7389, BRD-7389, 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione, 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione
- Molecular Weight:
- 366.4
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 376382-11-5
- ABP:
- No Import Docs
- Extra Details:
- BRD 7389 is a selective inhibitor of p90 ribosomal S6 kinases (RSK1, RSK2, and RSK3), key effectors in the MAPK/ERK signaling pathway. Although initially studied for its role in regulating insulin expression in pancreatic alpha-cells, BRD 7389's modulation of RSK activity has implications for neuroscience. RSK signaling influences neuronal survival, synaptic plasticity, and memory formation. Dysregulation of this pathway has been implicated in neurodegenerative diseases and cognitive disorders. By targeting RSKs, BRD 7389 may serve as a tool for dissecting the molecular mechanisms underlying neuronal function and resilience, offering potential leads for therapeutic development in neurodegeneration.
- Shipping Conditions:
- Ambient