SIH-486
Y 27632
Cannot supply to this region.
- SKU:
- SIH-486
- Additional Names:
- Y-27632 dihydrochloride, (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide . 2HCl
- Molecular Weight:
- 320.3
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 146986-50-7
- ABP:
- No Import Docs
- Extra Details:
- Y 27632 is a highly potent and selective inhibitor of Rho-associated protein kinases ROCK1 and ROCK2. It functions as an ATP-competitive inhibitor and is cell-permeable. In neurodegenerative disease research, Y 27632 is widely used to study cytoskeletal dynamics, axonal regeneration, and neuronal survival. By inhibiting ROCK signaling, Y 27632 promotes neurite outgrowth and reduces apoptosis, making it a promising compound for therapeutic strategies targeting spinal cord injury, Parkinson's disease, and other neurodegenerative conditions.
- Shipping Conditions:
- Ambient