SIH-472
Roscovitine
Cannot supply to this region.
- SKU:
- SIH-472
- Additional Names:
- 2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine, 2(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
- Molecular Weight:
- 354.4
- Purity:
- >99% (TLC and HPLC); NMR (Conforms)
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 186692-46-6
- ABP:
- No Import Docs
- Extra Details:
- Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK1/cyclin B, CDK2, and CDK5/p35. In neurodegenerative disease research, Roscovitine is widely used to study CDK5, a kinase implicated in tau phosphorylation, synaptic dysfunction, and neuronal death. It also affects calcium channel gating and promotes neuronal growth, making it a valuable tool for investigating cell cycle re-entry, neuroprotection, and regeneration in models of Alzheimer's and other neurodegenerative disorders.
- Shipping Conditions:
- Ambient