SIH-470
PP2
Cannot supply to this region.
- SKU:
- SIH-470
- Additional Names:
- 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Molecular Weight:
- 301.8
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 172889-27-9
- ABP:
- No Import Docs
- Extra Details:
- PP2 is a selective inhibitor of Src-family tyrosine kinases, including Lck, FynT, and Hck. It potently inhibits phosphorylation of focal adhesion kinase (FAK) and displays high selectivity over ZAP-70 and JAK2. In neurodegenerative disease research, PP2 is used to investigate the role of Src kinases in synaptic signaling, neuroinflammation, and blood-brain barrier integrity. Its application extends to models of Alzheimer's and multiple sclerosis, where Src-mediated pathways influence neuronal survival and immune responses.
- Shipping Conditions:
- Ambient