SIH-469
PP1
Cannot supply to this region.
- SKU:
- SIH-469
- Additional Names:
- 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Molecular Weight:
- 281.4
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 172889-26-8
- ABP:
- No Import Docs
- Extra Details:
- PP1 is a potent and selective inhibitor of Src family protein tyrosine kinases. It binds to the ATP-binding site of tyrosine and serine/threonine kinases, displaying high selectivity over ZAP-70 and JAK2. In neuroscience, PP1 is used to study the role of Src kinases in synaptic plasticity, neuronal development, and neuroinflammation. It is particularly useful in models of excitotoxicity and neurodegeneration, where Src signaling contributes to calcium dysregulation and cell death.
- Shipping Conditions:
- Ambient