SIH-460
Lestaurtinib
Cannot supply to this region.
- SKU:
- SIH-460
- Additional Names:
- KT5555, CEP-701, (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
- Molecular Weight:
- 439.5
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 111358-88-4
- ABP:
- No Import Docs
- Extra Details:
- Lestaurtinib is a potent inhibitor of JAK2, FLT3, and TrkA receptor tyrosine kinases. In neuroscience, it is used to study neurotrophic signaling and inflammatory pathways. By inhibiting TrkA, Lestaurtinib helps elucidate the role of nerve growth factor (NGF) signaling in neuronal survival and differentiation. Its inhibition of JAK2 also makes it relevant in models of neuroinflammation and cytokine signaling. Lestaurtinib is a valuable compound for investigating kinase-driven mechanisms in neurodegenerative diseases.
- Shipping Conditions:
- Ambient