SIH-459
Lapatinib
Cannot supply to this region.
- SKU:
- SIH-459
- Additional Names:
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
- Molecular Weight:
- 581.1
- Purity:
- ≥99%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 231277-92-2
- ABP:
- No Import Docs
- Extra Details:
- Lapatinib is a dual tyrosine kinase inhibitor that targets the ErbB2 (HER2) and epidermal growth factor receptor (EGFR) pathways. While primarily used in oncology, Lapatinib has potential applications in neuroscience due to the involvement of EGFR signaling in neuroinflammation, gliosis, and neurodegeneration. It is being explored for its ability to modulate glial cell activity and protect against excitotoxicity in models of Alzheimer's disease and brain injury. Lapatinib's ability to cross the blood-brain barrier enhances its utility in central nervous system research.
- Shipping Conditions:
- Ambient