SIH-456
K252B
Cannot supply to this region.
- SKU:
- SIH-456
- Additional Names:
- (9S, 10R, 12R)- 2, 3, 9, 10, 11, 12- hexahydro- 10- hydroxy- 9- methyl- 1- oxo- 9, 12- epoxy- 1H- diindolo[1, 2, 3- fg:3', 2', 1'- kl]pyrrolo[3, 4- i][1, 6]benzodiazocine- 10- carboxylic acid
- Molecular Weight:
- 453.5
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 99570-78-2
- ABP:
- No Import Docs
- Extra Details:
- K252B is a non-selective protein kinase inhibitor that targets CaMKII, MYLK, PKA, PKC, and cGKI by binding to the ATP-binding domain of these kinases. It is cell-permeable and used in neuroscience to study the regulation of intracellular signaling pathways involved in synaptic transmission, plasticity, and neuronal survival. K252B is particularly useful in dissecting the roles of calcium/calmodulin-dependent kinases and cyclic nucleotide-dependent kinases in neurodevelopment and neurodegeneration.
- Shipping Conditions:
- Ambient