SIH-454
JX 401
Cannot supply to this region.
- SKU:
- SIH-454
- Additional Names:
- 1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
- Molecular Weight:
- 355.5
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 349087-34-9
- ABP:
- No Import Docs
- Extra Details:
- JX 401 is a potent and reversible inhibitor of p38A Alpha mitogen-activated protein kinase (MAPK), a key regulator of inflammatory responses and cellular stress signaling. In neurodegenerative disease research, p38A Alpha MAPK is implicated in microglial activation, cytokine production, and neuronal apoptosis. JX 401 is used to investigate the role of p38A Alpha in neuroinflammation and neurotoxicity, particularly in models of Alzheimer's disease, Parkinson's disease, and traumatic brain injury. Its cell-permeable nature and specificity make it a valuable tool for dissecting MAPK signaling pathways in the central nervous system.
- Shipping Conditions:
- Ambient