SIH-451
GW5074
Cannot supply to this region.
- SKU:
- SIH-451
- Additional Names:
- 3-(3,5-Dibromo-4-hydroxybenzyliden)-5-iodo-1,3-dihydroindol-2-one
- Molecular Weight:
- 520.9
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 220904-83-6
- ABP:
- No Import Docs
- Extra Details:
- GW5074 is a potent and selective inhibitor of c-Raf1 kinase, showing over 100-fold selectivity over other kinases such as CDK1, ERK2, and VEGFR2. In neuroscience, GW5074 is used to study Raf/MEK/ERK signaling in neuronal survival, differentiation, and apoptosis. It has been shown to block low potassium-induced cell death and prevent neurodegeneration. GW5074's ability to modulate MAPK signaling makes it a key compound for exploring neuroprotective mechanisms and therapeutic targets in neurodegenerative diseases.
- Shipping Conditions:
- Ambient