SIH-449
GW2580
Cannot supply to this region.
- SKU:
- SIH-449
- Additional Names:
- 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-Pyrimidinediamine, 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine, GW 2580, GW-2580
- Molecular Weight:
- 366.4
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 870483-87-7
- ABP:
- No Import Docs
- Extra Details:
- GW2580 is a potent and selective ATP-competitive inhibitor of cFMS kinase, the receptor for macrophage colony-stimulating factor (M-CSF/CSF-1). In neurodegenerative disease research, GW2580 is used to study microglial activation and neuroinflammation, as CSF-1 signaling regulates immune cell proliferation and survival in the brain. By inhibiting cFMS, GW2580 helps elucidate the role of microglia in neurodegeneration and supports the development of anti-inflammatory therapies for conditions such as Alzheimer's and multiple sclerosis.
- Shipping Conditions:
- Ambient