GF109203X

Cannot supply to this region.

SKU:: SIH-447
Additional Names:: 2-[1-(3-Dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl) maleimide, 3-(N-[Dimethylamino]propyl-3-indolyl)-4-(3-indolyl)maleimide, 3-[1-[3-(Dimethylamino)propyl]1H-indol-3-yl]-4-(1Hindol-3-yl)1H-pyrrole-2,5dione, Bisindolylmaleimide I
Molecular Weight:: 412.5
Purity:: ≥98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 133052-90-1
ABP:: No Import Docs
Extra Details:: GF109203X is a potent and selective inhibitor of protein kinase C (PKC), particularly the A Alpha and B Beta1 isoforms. It also inhibits glycogen synthase kinase-3 (GSK-3) and exhibits anti-inflammatory effects. In neuroscience, GF109203X is used to study PKC and GSK-3 signaling in neuronal plasticity, neuroinflammation, and autophagy. Its ability to modulate kinase activity and telomerase function makes it a useful tool for investigating neurodegenerative processes and potential therapeutic interventions targeting kinase dysregulation.