SIH-442
Doramapimod
Cannot supply to this region.
- SKU:
- SIH-442
- Additional Names:
- JNK Inhibitor XVII, BIRB796, 1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea
- Molecular Weight:
- 527.7
- Purity:
- ≥99%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 285983-48-4
- ABP:
- No Import Docs
- Extra Details:
- Doramapimod is a highly potent and selective inhibitor of p38A Alpha mitogen-activated protein kinase (MAPK), a key regulator of inflammatory signaling. In neurodegenerative disease research, p38A Alpha MAPK is implicated in microglial activation, cytokine production, and neuronal stress responses. Doramapimod is used to explore the therapeutic potential of p38A Alpha inhibition in reducing neuroinflammation and protecting against neuronal damage in conditions such as Alzheimer's disease, ALS, and multiple sclerosis.
- Shipping Conditions:
- Ambient