SIH-436
Bml 277
Cannot supply to this region.
- SKU:
- SIH-436
- Additional Names:
- Chk2 Inhibitor II, Chk2 Inhibitor II hydrate, 2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide hydrate
- Molecular Weight:
- 363.8
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 516480-79-8
- ABP:
- No Import Docs
- Extra Details:
- Bml 277 is a highly selective inhibitor of checkpoint kinase 2 (Chk2), a key component of the DNA damage response pathway. In neuroscience, Chk2 is studied for its role in neuronal apoptosis and genomic stability under stress conditions. Bml 277 is used to investigate the contribution of Chk2 signaling to neurodegenerative processes, particularly in models of oxidative stress, ischemia, and neuroinflammation. Its selectivity makes it a valuable tool for dissecting DNA repair mechanisms and their impact on neuronal survival.
- Shipping Conditions:
- Ambient