SIH-433
AS 041164
Cannot supply to this region.
- SKU:
- SIH-433
- Additional Names:
- NSC31098, 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione
- Molecular Weight:
- 249.2
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 6318-41-8
- ABP:
- No Import Docs
- Extra Details:
- AS 041164 is a selective inhibitor of the PI3KG Gamma isoform, a key regulator of immune cell signaling and migration. In neuroscience, PI3KG Gamma has been implicated in neuroinflammatory responses and microglial activation, processes that contribute to the progression of neurodegenerative diseases. By blocking PI3KG Gamma activity, AS 041164 can modulate leukocyte trafficking and reduce neuroinflammation, making it a valuable tool for studying immune-mediated mechanisms in conditions such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease. Its ability to inhibit neutrophil migration further supports its application in models of neurovascular inflammation and blood-brain barrier dysfunction.
- Shipping Conditions:
- Ambient