SIH-416
MS-275
Cannot supply to this region.
- SKU:
- SIH-416
- Additional Names:
- Entinostat; 3-pyridinylmethyl [[4-[[(2-aminophenyl)amino]carbonyl]phenyl]methyl]carbamate, N-(2-Aminophenyl)-4-[N-(pyridine-3ylmethoxycarbonyl)aminomethyl]benzamide
- Molecular Weight:
- 376.4
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 209783-80-2
- ABP:
- No Import Docs
- Extra Details:
- MS 275 (Entinostat) is a selective inhibitor of class I histone deacetylases (HDACs), which regulate chromatin structure and gene expression. In neuroscience, MS 275 is used to study epigenetic mechanisms underlying neurodevelopment, synaptic plasticity, and neurodegeneration. HDAC inhibition by MS 275 promotes histone acetylation, leading to transcriptional activation of neuroprotective genes. It has shown promise in models of Alzheimer's and Huntington's disease by enhancing cognitive function and reducing neuroinflammation. MS 275 is a valuable tool for exploring epigenetic therapies aimed at restoring neuronal health and function.
- Shipping Conditions:
- Ambient