SIH-411
D-AP5
Cannot supply to this region.
- SKU:
- SIH-411
- Additional Names:
- D-amino-5-phosphonopentaoic acid
- Molecular Weight:
- 197.13
- Purity:
- >99.5%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 79055-68-8
- ABP:
- No Import Docs
- Extra Details:
- D-AP5 (D-(-)-2-Amino-5-phosphonopentanoic acid) is a selective, competitive antagonist of the NMDA receptor, specifically targeting the glutamate binding site. NMDA receptors are critical for synaptic plasticity, learning, and memory, but their overactivation leads to excitotoxicity-a key contributor to neuronal death in neurodegenerative diseases such as Alzheimer's, Huntington's, and ALS. D-AP5 is widely used in neuroscience to investigate NMDA receptor-mediated signaling, synaptic transmission, and neuroprotection. By blocking excitotoxic calcium influx, D-AP5 serves as a valuable tool for studying mechanisms of neuronal injury and for developing therapeutic strategies aimed at modulating glutamatergic dysfunction in the CNS.
- Shipping Conditions:
- Ambient