SIH-400
Hydroxychloroquine
Cannot supply to this region.
- SKU:
- SIH-400
- Additional Names:
- Hydroxychloroquine sulphate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline
- Molecular Weight:
- 433.95
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 747-36-4
- ABP:
- No Import Docs
- Extra Details:
- Hydroxychloroquine is a lysosomotropic agent known for its ability to inhibit autophagy by increasing lysosomal pH and preventing autophagosome-lysosome fusion. In neuroscience, hydroxychloroquine is used to study autophagic flux and lysosomal function in models of neurodegenerative diseases such as Alzheimer's and Parkinson's. By disrupting autophagy, it helps elucidate the role of protein clearance and organelle recycling in neuronal survival. Additionally, hydroxychloroquine exhibits immunomodulatory effects, making it relevant in neuroinflammation research. Its dual action on autophagy and immune signaling provides insights into the cellular mechanisms underlying neurodegeneration and offers potential therapeutic avenues for modulating disease progression.
- Shipping Conditions:
- Ambient