SIH-384
24(S)-Hydroxycholesterol
Cannot supply to this region.
- SKU:
- SIH-384
- Additional Names:
- (3B Beta,24S)-Cholest-5-ene-3,24-diol
- Molecular Weight:
- 402.7
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 474-73-7
- ABP:
- No Import Docs
- Extra Details:
- 24(S)-Hydroxycholesterol is a brain-derived oxysterol and a potent endogenous agonist of liver X receptors (LXRs), which regulate cholesterol homeostasis and inflammatory gene expression in the central nervous system. As a major cholesterol metabolite in the brain, it plays a critical role in maintaining neuronal lipid balance. Elevated levels of 24(S)-hydroxycholesterol in cerebrospinal fluid have been associated with early-stage Alzheimer's disease and mild cognitive impairment, making it a valuable biomarker for neurodegeneration. Additionally, its neurotoxic effects on neuronal cells underscore its dual role as both a physiological regulator and a potential contributor to disease pathology.
- Shipping Conditions:
- Ambient