SIH-370
Xanthohumol
Cannot supply to this region.
- SKU:
- SIH-370
- Additional Names:
- (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(-3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)--2-propen-1-one
- Molecular Weight:
- 354.4
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 6754-58-1
- ABP:
- No Import Docs
- Extra Details:
- Xanthohumol is a prenylated flavonoid and valosin-containing protein (VCP) inhibitor that has shown promise in neurodegenerative disease research. By binding to the N-domain of VCP, it disrupts autophagosome maturation, a process critical for cellular waste clearance in neurons. Impaired autophagy is a hallmark of neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Xanthohumol also exhibits potent anticancer activity by inhibiting cell proliferation and inducing apoptosis. Its dual role in modulating proteostasis and cell survival pathways makes it a valuable tool for investigating therapeutic interventions in neurodegeneration.
- Shipping Conditions:
- Ambient