SIH-366
PJ-34
Cannot supply to this region.
- SKU:
- SIH-366
- Additional Names:
- N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,Ndimethylacetamide . HCl
- Molecular Weight:
- 331.8
- Purity:
- ≥98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 344458-15-7
- ABP:
- No Import Docs
- Extra Details:
- PJ-34 is a potent inhibitor of poly(ADP-ribose) polymerase (PARP), an enzyme involved in DNA repair and cell death pathways. In neuroscience, PJ-34 is used to study neuroprotection in models of ischemia, traumatic brain injury, and neurodegeneration. PARP overactivation leads to energy depletion and neuronal death, and PJ-34 mitigates this by preserving cellular NAD⁺ levels. Its anti-inflammatory and anti-apoptotic effects make it a valuable compound for exploring therapeutic strategies aimed at reducing neuronal damage and promoting recovery in neurodegenerative conditions.
- Shipping Conditions:
- Ambient