SIH-355
Garcinol
Cannot supply to this region.
- SKU:
- SIH-355
- Additional Names:
- Camboginol, 3- (3, 4- dihydroxybenzoyl)- 4- hydroxy- 8, 8- dimethyl- 1, 7- bis(3- methyl- 2- buten- 1- yl)- 5- [(2S)- 5- methyl- 2- (1- methylethenyl)- 4- hexen- 1- yl]- bicyclo[3.3.1]non- 3- ene- 2, 9- dione
- Molecular Weight:
- 602.8
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 78824-30-3
- ABP:
- No Import Docs
- Extra Details:
- Garcinol is a natural, cell-permeable inhibitor of histone acetyltransferases p300 and pCAF (IC₅₀ = 7 uM and 5 uM, respectively). It induces apoptosis, promotes hematopoietic stem cell expansion, and exhibits anti-inflammatory properties. In neuroscience, Garcinol has been shown to promote neurogenesis in cortical progenitor cells and suppress neuroinflammation in Alzheimer's models by modulating NF-K KappaB signaling. Its ability to regulate histone acetylation and transcriptional activity positions it as a promising compound for exploring epigenetic therapies in neurodegenerative diseases.
- Shipping Conditions:
- Ambient