SIH-354
FK-866 HCl
Cannot supply to this region.
- SKU:
- SIH-354
- Additional Names:
- (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-(pyridin-3-yl)acrylamide, FK866 hydrochloride hydrate, K22.175
- Molecular Weight:
- 428
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 658084-64-1
- ABP:
- No Import Docs
- Extra Details:
- FK-866 HCl is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme involved in NAD⁺ biosynthesis. In neuroscience, FK-866 is used to study the role of NAD⁺ metabolism in neuronal survival, energy homeostasis, and neuroinflammation. NAD⁺ depletion induced by FK-866 leads to mitochondrial dysfunction and cell death, providing a model for investigating neurodegenerative mechanisms. Its application extends to exploring therapeutic strategies that target metabolic resilience and oxidative stress in neurodegenerative diseases.
- Shipping Conditions:
- Ambient