SIH-336
Thalidomide
Cannot supply to this region.
- SKU:
- SIH-336
- Additional Names:
- (+/-)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, N-(2,6-dioxo-3-piperidinyl)phthalim-ide
- Molecular Weight:
- 258.2
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 50-35-1
- ABP:
- No Import Docs
- Extra Details:
- Thalidomide binds to the E3 ubiquitin ligase complex involving CRBN, DDB1, and Cul4A, inhibiting ligase activity. It suppresses TNF synthesis and angiogenesis. In neuroscience, Thalidomide is explored for its immunomodulatory effects and potential to modulate neuroinflammation and neurovascular integrity, although caution is warranted due to its teratogenic properties.
- Shipping Conditions:
- Ambient