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SIH-331

mlN4924

Cannot supply to this region.

SKU:
SIH-331
Additional Names:
[(1S,2S,4R)-4-{4-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-2-hydroxycyclopentyl]methyl sulfamate, Sulfamic acid
Molecular Weight:
443.2
Purity:
>98%
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
CAS Number:
905579-51-3
ABP:
No Import Docs
Extra Details:
MLN4924 is a potent and selective inhibitor of the NEDD8-activating enzyme (NAE), disrupting cullin-RING ligase-mediated protein turnover. It induces apoptosis and suppresses tumor growth. In neuroscience, MLN4924 is used to explore the role of neddylation in neural development, neuroinflammation, and neurodegeneration.
Shipping Conditions:
Ambient