SIH-326
MG-132
Cannot supply to this region.
- SKU:
- SIH-326
- Additional Names:
- N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-L-leucinamide, Z-Leu-Leu-Leu-al, Z-LLL-CHO, N- [(phenylmethoxy)carbonyl]- L- leucyl- N- [(1S)- 1- formyl- 3- methylbutyl]- L- leucinamide
- Molecular Weight:
- 475.6
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 133407-82-6
- ABP:
- No Import Docs
- Extra Details:
- MG-132 is a specific inhibitor of the 20S proteasome, blocking NF-K KappaB activation by preventing IK KappaB proteolysis. It stimulates autophagy and induces the heat shock response, making it a valuable tool in studying protein degradation and stress pathways. In neuroscience, MG-132 is used to investigate proteostasis, neuroinflammation, and the role of ubiquitin-proteasome system dysfunction in neurodegenerative diseases.
- Shipping Conditions:
- Ambient