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SIH-325

Pifithrin mu

Cannot supply to this region.

SKU:
SIH-325
Additional Names:
2-Phenylethynesulfonamide, PFTu
Molecular Weight:
181.2
Purity:
>98%
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
CAS Number:
64984-31-2
ABP:
No Import Docs
Extra Details:
Pifithrin mu selectively interacts with HSP70, disrupting its association with co-chaperones and substrate proteins. It inhibits p53 binding to mitochondria by reducing its affinity for antiapoptotic proteins Bcl-2 and Bcl-XL. This dual action promotes apoptosis and modulates stress response pathways. In neurodegenerative research, Pifithrin mu is used to study protein folding, mitochondrial integrity, and apoptotic regulation.
Shipping Conditions:
Ambient