SIH-257
Simvastatin
Cannot supply to this region.
- SKU:
- SIH-257
- Additional Names:
- (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate
- Molecular Weight:
- 418.57
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 79902-63-9
- ABP:
- No Import Docs
- Extra Details:
- Simvastatin is a lipid-lowering agent belonging to the statin class, primarily used to reduce cholesterol levels and prevent cardiovascular disease. In neuroscience, simvastatin has garnered interest for its potential neuroprotective effects. It inhibits HMG-CoA reductase, thereby reducing the synthesis of cholesterol and isoprenoids-molecules involved in protein prenylation and cellular signaling. This mechanism may influence neuroinflammation, oxidative stress, and amyloid-beta accumulation, all of which are implicated in neurodegenerative diseases such as Alzheimer's. Simvastatin's ability to cross the blood-brain barrier further supports its potential as a therapeutic agent in neurological disorders.
- Shipping Conditions:
- Ambient