SIH-251
Deguelin
Cannot supply to this region.
- SKU:
- SIH-251
- Additional Names:
- (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
- Molecular Weight:
- 394.42
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 522-17-8
- ABP:
- No Import Docs
- Extra Details:
- Deguelin is a rotenoid compound with notable anti-cancer and neurotoxic properties. It inhibits mitochondrial complex I, leading to increased oxidative stress and apoptosis in cancer cells. However, its neurotoxicity has raised concerns, particularly due to its association with Parkinsonian symptoms in animal models. Deguelin's dual role as a therapeutic agent and neurotoxin makes it a compound of interest in neurodegenerative disease research, especially for understanding mitochondrial dysfunction and oxidative stress pathways in dopaminergic neurons.
- Shipping Conditions:
- Ambient