SIH-243
Irinotecan HCl
Cannot supply to this region.
- SKU:
- SIH-243
- Additional Names:
- (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl 1,4'-bipiperidine-1'-carboxylate, CPT11, Camptothecin 11
- Molecular Weight:
- 623.14
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 100286-90-6
- ABP:
- No Import Docs
- Extra Details:
- Irinotecan is a semisynthetic analogue of camptothecin that inhibits topoisomerase I. It is converted to its active metabolite SN-38, which interferes with DNA replication and transcription. In neurobiology, irinotecan is used to study DNA damage responses and has potential applications in understanding neuronal vulnerability to genotoxic stress.
- Shipping Conditions:
- Ambient