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SIH-242

Camptothecin

Cannot supply to this region.

SKU:
SIH-242
Additional Names:
(4S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Molecular Weight:
348.36
Purity:
>98%
Source:
Synthetic
Storage Conditions:
-20[o]C
Supplier:
StressMarq Biosciences
CAS Number:
7689-03-4
ABP:
No Import Docs
Extra Details:
Camptothecin is a cytotoxic quinoline alkaloid that inhibits topoisomerase I, stabilizing the DNA-topoisomerase complex and preventing DNA re-ligation. This leads to DNA damage and apoptosis. In neuroscience, camptothecin is used to model DNA damage-induced neuronal death and to explore mechanisms of genomic instability in neurodegenerative diseases.
Shipping Conditions:
Ambient