Nigericin

Cannot supply to this region.

SKU:: SIH-229
Additional Names:: (2R)-2-[(2R,3S,6R)-6-{[(2S,4R,5R,7R,9R,10R)-2-{(2S,2'R,3'S,5R,5'R)-5'-[(2S,3S,5R,6R)-6-Hydroxy-6-(hydroxymethyl)-3,5-dimethyltetrahydro-2H-pyran-2-yl]-2,3'-dimethyloctahydro-2,2'-bifuran-5-yl}-9-metho xy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]dec-7-yl]methyl}-3-methyltetrahydro-2H-pyran-2-yl]propanoic acid
Molecular Weight:: 746.94
Purity:: >98%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 28643-80-3
ABP:: No Import Docs
Extra Details:: Nigericin is a potassium and sodium ionophore that disrupts mitochondrial membrane potential and stimulates calcium release from mitochondrial stores. In neuroscience, it is used to study mitochondrial dysfunction, a hallmark of many neurodegenerative diseases. By altering ion gradients, nigericin helps elucidate the role of mitochondrial signaling and bioenergetics in neuronal health and disease.