SIH-214
FK506
Cannot supply to this region.
- SKU:
- SIH-214
- Additional Names:
- 3-(3-Pyridinyl)propyl 1-(3,3-dimethyl-2-oxopentanoyl)prolinate, Tacrolimus, Fujimycin
- Molecular Weight:
- 804
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 104987-11-3
- ABP:
- No Import Docs
- Extra Details:
- FK506, also known as Tacrolimus or Fujimycin, is a macrolide immunosuppressant with emerging neuroprotective properties. It inhibits calcineurin by forming a complex with FKBP12, thereby preventing NF-AT dephosphorylation and downstream T-cell activation. In neuroscience, FK506 has shown promise in protecting neurons from degeneration in models of antiretroviral toxic neuropathy and other neuroinflammatory conditions. Its ability to modulate calcium signaling and reduce neuroinflammation positions it as a potential therapeutic agent for neurodegenerative diseases.
- Shipping Conditions:
- Ambient