Cyclosporine

Cannot supply to this region.

SKU:: SIH-201
Additional Names:: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,3 1-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, Cyclosporin A
Molecular Weight:: 1202.63
Purity:: >99%
Source:: Synthetic
Storage Conditions:: -20[o]C
Supplier:: StressMarq Biosciences
CAS Number:: 59865-13-3
ABP:: No Import Docs
Extra Details:: Cyclosporine A is a cyclic peptide immunosuppressant that inhibits calcineurin, thereby preventing the activation of NF-AT and downstream T-cell responses. In neuroscience, cyclosporine has been investigated for its neuroprotective effects, particularly in models of traumatic brain injury, stroke, and neurodegenerative diseases. By inhibiting mitochondrial permeability transition pore (mPTP) opening, cyclosporine helps preserve mitochondrial integrity and prevent apoptosis in neurons. Its ability to modulate calcium signaling and reduce oxidative stress makes it a promising agent for protecting neural tissue under pathological conditions.