SIH-182
J9
Cannot supply to this region.
- SKU:
- SIH-182
- Additional Names:
- 4-cyclopropyl-5-(pyridin-4-yl)pyrimidin-2-amine
- Molecular Weight:
- 212.26
- Purity:
- 99.9%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- ABP:
- No Import Docs
- Extra Details:
- J9 is a small molecule that enhances glucocorticoid receptor expression, thereby sensitizing T-cell acute lymphoblastic leukemia (T-ALL) cells to dexamethasone. While primarily studied in oncology, its mechanism of modulating steroid receptor pathways may have implications in neuroinflammation and stress-related neural disorders. Glucocorticoid signaling plays a role in brain function and resilience to stress, suggesting that J9 could be explored for its potential to modulate neuroendocrine responses in psychiatric and neurodegenerative conditions.
- Shipping Conditions:
- Blue Ice