SIH-123
115-7C
Cannot supply to this region.
- SKU:
- SIH-123
- Additional Names:
- 4-(5-((benzyloxy)carbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid, SWO2
- Molecular Weight:
- 477.34
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- ABP:
- No Import Docs
- Extra Details:
- 115-7C is a small molecule that activates the ATPase activity of Hsp70 and promotes substrate refolding. It binds to the IIA subdomain of DnaK and enhances the formation of the DnaK-DnaJ complex. In neurodegenerative disease research, 115-7C is of interest for its role in maintaining proteostasis and preventing protein aggregation. By stimulating Hsp70's chaperone activity, 115-7C may help mitigate the accumulation of misfolded proteins such as tau and alpha-synuclein, which are central to the pathology of Alzheimer's and Parkinson's diseases.
- Shipping Conditions:
- Ambient