SIH-116
Herbimycin A
Cannot supply to this region.
- SKU:
- SIH-116
- Additional Names:
- [(2R,3S,5S,6R,7S,8E,10S,11S,12E,14E)-2,5,6,11-tetramethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate
- Molecular Weight:
- 574.3
- Purity:
- >98%
- Source:
- Synthetic
- Storage Conditions:
- -20[o]C
- Supplier:
- StressMarq Biosciences
- CAS Number:
- 70563-58-5
- ABP:
- No Import Docs
- Extra Details:
- Herbimycin A is a benzoquinoid ansamycin antibiotic known for its irreversible inhibition of tyrosine kinases through thiol group interaction. While predominantly studied in oncology, Herbimycin A's ability to modulate kinase signaling cascades positions it as a candidate for neurodegenerative disease research. Tyrosine kinases play critical roles in neuronal survival, synaptic plasticity, and neuroinflammation. By inhibiting kinases such as Src and Abl, Herbimycin A may help attenuate aberrant signaling associated with neurodegenerative conditions. Its potential to influence phospholipase C activity and downstream pathways further supports its relevance in neuroscience, particularly in the context of cellular stress responses and neuroprotection.
- Shipping Conditions:
- Ambient