Mouse Chordin ELISA Kit

Cannot supply to this region.

SKU:: KOA0845
Additional Names:: Chordin, Chrd, CHRD_HUMAN, MGC133038, Shortgastrulation protein, SOG|CHRD
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Mouse
Immunogen:: Expression system for standard: NSO; Immunogen sequence: T27-S948
Species:: Mouse
Uniprot:: Q9Z0E2
Synonyms:: Chd;chordin
Extra Details:: Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. In mice, Chordin is expressed in the node but not in the anterior visceral endoderm. It has been found to be required for forebrain development. In developing mice that are deficient in both chordin and noggin, the head is nearly absent. This is significant because when only noggin is deficient there are mild defects but the head still forms. Chordin is also involved in avian gastrulation. It is expressed in the anterior cells of Koller's sickle, which form the anterior cells of the primitive streak, a key structure through which gastrulation occurs.