Human Biglycan ELISA Kit

Cannot supply to this region.

SKU:: KOA0820
Additional Names:: BGN|BGN, Biglycan, Biglycan proteoglycan, Bone/cartilage proteoglycan I, Dermatan sulphate proteoglycan I, DSPG1, PG S1, PG-S1, PGI, PGS1_HUMAN, SLRR1A, Small leucine rich protein 1A
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: D38-K368
Species:: Human
Uniprot:: P21810
Synonyms:: biglycan;Bone/cartilage proteoglycan I;bone/cartilage proteoglycan-I;dermatan sulphate proteoglycan I;DSPG1;MRLS;PG-S1;PGI;SEMDX;SLRR1A;small leucine-rich protein 1A
Extra Details:: Biglycan (BGN) is a small leucine-rich repeat proteoglycan (SLRP) which is found in a variety of extracellular matrix tissues, including bone, cartilage and tendon. It is an important structural component of articular cartilage and participates in the assembly of the chondrocyte extracellular matrix through formation of protein interactions with type VI collagen and large proteoglycan aggregates. In humans, Biglycan is encoded by the BGN gene. It is mapped to Xq28. Biglycan is believed to play a role in the mineralisation of bone, and its core protein binds to the growth factors BMP-4 and influences its bioactivity. It has been reported that the presence of biglycan is necessary for BMP-4 to exert its effects on osteoblasts. There is also evidence that biglycan can bind to TGF-beta 1. In addition, Biglycan plays an important role in cell signaling.

Shipping Conditions:: Blue Ice