Human DKK-3 ELISA Kit

Cannot supply to this region.

SKU:: KOA0794
Additional Names:: AW061014, C87148, Dickkopf (Xenopus laevis) homolog 3, Dickkopf 3, Dickkopf homolog 3 (Xenopus laevis), Dickkopf related protein 3, HDkk 3, Regulated in glioma, REIC, RIG, RIG like 5 6, RIG like 7 1|DKK3
Application:: ELISA
Storage Conditions:: Please refer to datasheet
Supplier:: Rockland Inc
Reactivities:: Human
Immunogen:: Expression system for standard: NSO; Immunogen sequence: A22-I350
Species:: Human
Uniprot:: Q9UBP4
Synonyms:: dickkopf 3 homolog;dickkopf homolog 3;dickkopf-3;dickkopf-related protein 3;dkk-3;hDkk-3;regulated in glioma;REIC;RIG;RIG-like 5-6;RIG-like 7-1
Extra Details:: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

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