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KOA0764

Human CRLF2 - TSLP R ELISA Kit

Cannot supply to this region.

SKU:
KOA0764
Additional Names:
CRL 2, CRL2, CRLF 2, Crlf2, CRLF2_HUMAN, CRLF2Y, Cytokine receptor CRL2 precursor, Cytokine receptor like 2, Cytokine receptor like factor 2, Cytokine receptor like factor 2 precursor, Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL XR, IL-XR, ILXR, Thymic stromal derived lymphopoietin receptor, Thymic stromal lymphopoietin protein receptor, Thymic stromal lymphopoietin receptor, TSLP receptor, TSLPR|CRLF2
Application:
ELISA
Storage Conditions:
Please refer to datasheet
Supplier:
Rockland Inc
Reactivities:
Human
Immunogen:
Expression system for standard: NSO; Immunogen sequence: G25-K231
Species:
Human
Uniprot:
Q9HC73
Synonyms:
CRL2;CRLF2Y;cytokine receptor CRL2 precusor;Cytokine receptor-like 2;cytokine receptor-like factor 2;IL-XR;thymic stromal lymphopoietin protein receptor;thymic stromal-derived lymphopoietin receptor;TSLP receptor;TSLPR
Extra Details:
Cytokine receptor-like factor 2, also known as TSLPR or CRL2, is a protein that in humans is encoded by the CRLF2 gene. It is mapped to Xp22.33. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin(TSLP). Together with the interleukin 7 receptor(IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. In addition to it, it has been found that rearrangement of CRLF2 and JAK mutation together contribute to leukemogenesis in B-progenitor ALL.
Shipping Conditions:
Blue Ice